Searching for keyword:"Surgery--Complications"

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US Clinical Trial NCT03959904 – NIH – Apr 8, 2019

The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation

Study Design This study has two phases. In phase 1 we will perform a retrospective review of hernia incidence in our centre over the last decade. We will seek to identify risk factors in our transplant cohort. In phase 2 we will perform a prospectiv...
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US Clinical Trial NCT03923127 – NIH – Apr 17, 2019

PJ-013483 FLAGSHIP Transitional Care Study 3

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US Clinical Trial NCT01860053 – NIH – May 6, 2013

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US Clinical Trial NCT03720834 – NIH – Oct 17, 2018

What is the Numerical Translation of Verbal Probability Expressions Used by Patients and Doctors in the Context of Communication of Peri-operative Risk?

Shared decision-making is central to the consent process prior to surgery and anaesthesia. Verbal probability expressions are commonly used by clinicians to help describe the level of risk. Common examples of verbal probability expressions are shown...
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US Clinical Trial NCT03144973 – NIH – May 3, 2017

Meaning of Periodontitis in Post-operative Complications After Upper Gastrointestinal Tract Surgery

Before patricipating patients go to preop, the investigators have them take a mouth rinsing quick-test, periosafe(c), that tells specifically about periodontitis. Participants go to surgery (upper gi) and have a normal operation following our clinic...
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US Clinical Trial NCT03376542 – NIH – Nov 22, 2017

Cardiopulmonary Exercise Testing as an Outcome Predictor in Coronary Artery Bypass Surgery

Coronary artery bypass surgery (CABG) is a complex and expensive procedure with great potential for morbidity and mortality. Preoperative evaluation is of paramount importance to optimize results. There is much evidence about the benefits of the car...
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US Clinical Trial NCT03246165 – NIH – Aug 7, 2017

Incidence, Predictive Factors and Complications of Delirium in Postoperative Cardiac Surgery Elderly Patients

Delirium is a transient and fluctuating course syndrome of acute onset that is characterized by reduced level of consciousness, global cognitive dysfunction, and disorder in the sleep-wake cycle. In patients undergoing cardiac surgery, delirium is a...
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US Clinical Trial NCT03205384 – NIH – Feb 22, 2017

Analysis of Morbimortality and Functional Status in Older Patients(>65 Years Old) Undergoing Urgent Abdominal Surgery Using CRISTAL Score Modify

the investigor will register the morbimotality after 6 months of follow up, in patient older than 65 year old using the CRISTAL score modify, undergoing abdominal surgery. The measure the investigators are using are: Barthel scale, Frail score, Mini...
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US Clinical Trial NCT03721471 – NIH – Oct 2, 2018

Outcome of Very Old Patients Admitted for Elective Major Surgery, the Effect of Frailty

Patients ≥ 80 years admitted for elective major abdominal surgery will be asked to participate in this study where frailty will be scored using the Clinical Frailty Scale and by measuring hand-grip-strength. Primary outcome is mortality at 30 days,...
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US Clinical Trial NCT03483181 – NIH – Mar 19, 2018

Thromboprophylaxis in Patients Undergoing Orthopedic Surgeries; Using Propensity Score Matching

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US Clinical Trial NCT03044899 – NIH – Feb 3, 2017

African Surgical Outcomes Study (ASOS): An African, Multi-centre Seven Day Evaluation of Patient Care and Clinical Outcomes for Patients Undergoing Surgery

Research questions Primary objective To confirm the incidence of in-hospital postoperative complications in adult surgical patients in Africa Secondary objectives 1. To confirm the rate of mortality on the day of surgery for patients undergoing su...
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US Clinical Trial NCT03605134 – NIH – Jun 28, 2018

The Impact of Routine Measurement of Cardiac Troponin (hsTnT) on Outcome in Elderly Patients Undergoing Major Surgery

Elevated troponin (Tn) hsTnT levels occur as a result of myocardial damage and are used in the diagnosis of myocardial infarction (MI). However, there are multiple different causes that also result in abnormal Tn levels, such as direct myocardial-ce...
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US Clinical Trial NCT03211715 – NIH – Jun 20, 2017

Validation of Low Anterior Resection Syndrome Score in Korean Version

In this study, the low anterior resection syndrome score questionnaire proposed by Therese Juul is translated to Korean language by 3 different professional translators. Patients who received sphincter saving surgery to treat rectal cancer will be a...
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US Clinical Trial NCT03314623 – NIH – Oct 9, 2017

Immediate Mobilization After Plate Osteosynthesis of Proximal Tibial Fractures - A Cohort Study

The purpose of this study is to investigate immediate mobilization with weight bearing as tolerated following plate osteosynthesis after a proximal tibial plateau fracture is possible without increased risk of loss of reduction and/or failure of the...
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US Clinical Trial NCT02049372 – NIH – Jan 27, 2014

Developing a Prospective Registry for Complications in Otorhinolaryngologic Surgery: Tonsil Surgery as a Pilot Cohort

In a six-month period all patients undergoing tonsillectomy or tonsillotomy with or without adenoidectomy were assessed for enrolment. Demographic and clinical data were recorded prospectively in a database which included 57 variables, such as age,...
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US Clinical Trial NCT03971851 – NIH – May 31, 2019

Testing and Validation of a Novel Frailty Index in a Surgical Cohort

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US Clinical Trial NCT00846261 – NIH – Feb 17, 2009

The Infected Bone Nonunion and Soft Tissue Defect of Long Bone Treated Simultaneously With Ilizarov Technique

From January 2002 to now, totally 22 patients (18 males, 4 females) were underwent internal bone transport for infected nonunion in the long bone with soft-tissue defects. The mean age of the patients was 36.5 years (range, 19 to 57). The infected n...
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US Clinical Trial NCT03315195 – NIH – Oct 5, 2017

A Randomized Controlled Trial Comparing Postoperative Complication Between Preoperative Oral Nutritional Supplement With Dietary Advice and Conventional Dietary Advice Alone in Patients Undergoing Elective Major Gastrointestinal Surgery

The study design is a randomized controlled study. The eligible criteria is all patients who undergoing major gastrointestinal surgery including upper/lower gastrointestinal tract and hepatobiliary and pancratic surgery. After the informed consent a...
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US Clinical Trial NCT03771456 – NIH – Dec 6, 2018

Anastomotic Leakage and Enhanced Recovery Pathways After Colorectal Surgery: the Italian ColoRectal Anastomotic Leakage Study Group (iCral 2)

BACKGROUND Anastomotic leakage (AL) is a dreaded major complication after colorectal surgery. The overall incidence of anastomotic dehiscence and subsequent leaks is 2 to 7 percent when performed by experienced surgeons. The lowest leak rates are f...
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US Clinical Trial NCT03157479 – NIH – May 12, 2017

Intraoperative Protective Ventilation for Obese Patients Undergoing Gynaecological Laparoscopic Surgery. A Single-centre Randomized, Controlled Trial

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US Clinical Trial NCT03067909 – NIH – Feb 25, 2017

THE Management of AntiThrOMbotic therApy in Patients Undergoing Electrophysiological Device Surgery: Italian NatiOnal Multicenter Observational REgistry (HEMATOMA NO MORE)

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US Clinical Trial NCT03577613 – NIH – May 15, 2018

Radical Hysterectomy: Evolution Of Surgical Approach and Related Outcomes

Study Objective: To analyse the effect that the introduction of minimally invasive procedures has had on surgical and oncological outcomes when compared with conventional open radical hysterectomy (ORH) in a national reference cancer center Design:...
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US Clinical Trial NCT03751579 – NIH – Nov 8, 2018

Validation of the Respiratory Quotient Measurement Measured Indirectly in Coelioscopic Surgery

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US Clinical Trial NCT03914976 – NIH – Apr 9, 2019

Association of the Arteriovenous Difference in Carbon Dioxide and Its Relation to the Difference in Arteriovenous Oxygen Content With the Occurrence of Postoperative Complication

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US Clinical Trial NCT03317561 – NIH – Oct 18, 2017

Etiology of Myocardial Injury Following Non-cardiac Surgery - a Prospective Clinical Trial

Introduction: It is estimated that > 200 million patients in the world undergo surgery each year of which approximately 10 million would suffer from a myocardial injury in the perioperative period. Mortality is high in this group of patients sin...
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US Clinical Trial NCT03930784 – NIH – Apr 24, 2019

A Real-world Study to Examine the Relationship Between Simple Physical Functioning Tests, Complications and Recovery Following Abdominal Surgery - a Prospective Cohort Study

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US Clinical Trial NCT03113565 – NIH – Apr 10, 2017

Connected Electronic Wrist Strap for Patient Follow-up After Cardiac Surgery

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US Clinical Trial NCT03177070 – NIH – May 15, 2017

Investigating the Use of Fluorescent Imaging and Methylene Blue to Identify and Prevent Ureteric Injuries During Laparoscopic and Open Colorectal Surgery

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US Clinical Trial NCT03299296 – NIH – Sep 19, 2017

Thromboprophylaxis in Patients Undergoing Orthopedic Surgeries; Focus on Cost-effective Analysis and Safety Comparison Between Rivaroxaban and Enoxaparin

There is a Today consensus that patients undergoing high-risk surgery should receive prophylaxis against postoperative venous thromboembolism (VTE). A good example of that could be orthopedic surgeries which place patients at unnecessary increased r...
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US Clinical Trial NCT03518372 – NIH – Apr 24, 2018

Myocardial Injury and Intraoperative Tissue Oximetry in Patients Undergoing Spine Surgery (MONITOR)

Significance: Each year 10 million people worldwide suffer from myocardial injury after non-cardiac surgery (MINS). The majority of these events are undetected because they are asymptomatic and there is sparse knowledge about triggering causes. Maj...
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US Clinical Trial NCT03724123 – NIH – Oct 25, 2018

Machine Learning-Based Risk Profile Classification of Patients Undergoing Elective Heart Valve Surgery

The investigators performe a monocentric retrospective study in patients who underwent elective heart valve surgery between January 1, 2008, and December 31, 2014 at our center. The investigators use random forests, artificial neural networks, and s...
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US Clinical Trial NCT03963427 – NIH – May 21, 2019

GoBreast - a Prospective Randomized Trial on Breast Reconstruction Methods

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US Clinical Trial NCT03738085 – NIH – Nov 8, 2018

Previous Abdominal Surgery and Obesity Does Not Affect Unfavorably the Outcome of Total Laparoscopic Hysterectomy

Abstract: Objective: To assess the effects of previous abdominal surgery and obesity on the intra-operative and post-operative outcomes of total laparoscopic hysterectomy (TLH). Method: In this retrospective cohort study, women who underwent TLH f...
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US Clinical Trial NCT03812861 – NIH – Jan 14, 2019

Cognitive Aids for the Management of Deteriorating Surgical Patients

INTRODUCTION AND RATIONALE The suboptimal management of deteriorating surgical patients is an important factor in preventable death and morbidity in hospitals. Several studies have shown that the mortality rate in different hospitals is not associa...
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US Clinical Trial NCT03949348 – NIH – May 13, 2019

Transobturator Urethral Sling Placement With an Autologous Rectus Facia for Female Stress Urinary Incontinence.

Stress urinary incontinence (SUI) is very common condition in middle-aged women, and can affect quality of life. Some clinical trials reported that the lifetime risk of a woman undergoing surgery for SUI is increase in up to 15%. The midurethral syn...
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US Clinical Trial NCT03978325 – NIH – May 17, 2019

Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Oesophagus

Patients with cancer of the lung or oesophagus, undergoing curative treatment, usually require a thoracotomy and a complex oncological resection. These surgeries carry a risk of major morbidity and mortality, and risk assessment, preoperative optimi...
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US Clinical Trial NCT03757455 – NIH – Nov 13, 2018

Enhanced Recovery Versus Standard Recovery After Low-risk Pancreatoduodenectomy Identified With Acinar Cell Count or Total Pancreatectomy: a Randomized Controlled Trial

In the study, the enhanced recovery after surgery (ERAS) program is applied to total pancreatectomy (TP) and low-risk pancreaticoduodenectomy (PD) patients identified by a small number of acinar cells in the cut edge of the pancreas. The research se...
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US Clinical Trial NCT03851965 – NIH – Dec 17, 2018

A Prospective Observational Study on Assessment of the Soluble Urokinase Plasminogen Activator Receptor in Adult Patients Undergoing Major Non-cardiac Surgery

BACKGROUND Soluble urokinase plasminogen activator receptor The biomarker soluble urokinase plasminogen activator receptor (suPAR) is the soluble form of the cell membrane-bound protein urokinase plasminogen activator receptor (uPAR), which is exp...
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US Clinical Trial NCT03793816 – NIH – Jan 1, 2019

Tonsillectomy Using BiZact™ - a Randomized Side-controlled Clinical Trial

Although stricter indication criteria have been implanted (especially in Austria since 2008), tonsillectomies are still performed very frequently. Post-surgical bleeding can potentially be life-threatening, and occur within 3 weeks after tonsillecto...
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US Clinical Trial NCT03200600 – NIH – Jun 25, 2017

Impact of Perioperative Dexamethasone and Flurbiprofen Axetil on Delirium After Surgery for Non-small Cell Lung Cancer: A 2x2 Factorial Randomized Controlled Trial

Delirium is an acutely occurred, transient and fluctuating central nervous system dysfunction which is characterized by cognitive dysfunction, decreased level of consciousness, decentralized attention, and/or disturbed perception. It is a common com...
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US Clinical Trial NCT02771574 – NIH – May 6, 2016

A Phase 2 Multi-Ascending Dose Trial to Assess the Efficacy, Tolerability and Pharmacokinetic Profile of Exendin (9-39) in Patients With Post-bariatric Hyperinsulinemic Hypoglycemia

Post-Bariatric Hypoglycemia (PBH) is a rare, but increasingly reported disease occurring after bariatric surgery, characterized by severe hypoglycemic episodes accompanied by symptoms of hypoglycemia. At the moment, no medical therapies have been de...
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US Clinical Trial NCT03561376 – NIH – May 7, 2018

Zinc Oxide Versus Petrolatum Following Skin Surgery: A Head-to-head, Prospective, Split-scar Study

Patients who have undergone dermatologic excision for any indication with or without Mohs micrographic surgical technique and surgically closed in linear fashion with scar length of greater than or equal to 7 cm on any site but the scalp will be app...
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US Clinical Trial NCT03942146 – NIH – May 5, 2019

Smoking Cessation Prior to Gynecological Surgery - a Registry-based Randomized Trial

Peri-operative smoking cessation should be introduced 4-6 weeks before surgery and continued 4-6 weeks after surgery to decrease postoperative complications. The purpose of the study is to increase the exposure to smoking cessation information pior...
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US Clinical Trial NCT03949439 – NIH – May 12, 2019

Pre-frailty Status Increases the Risk of Rehospitalization and Mortality in Patients After Cardiac Surgery Without Complications

A three-year retrospective study based on a physiotherapy database was conducted, and a sample of 453 patients over 65 years of age was enrolled. All of them had an established diagnosis of cardiovascular disease (myocardial infarction, valve regurg...
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US Clinical Trial NCT03307096 – NIH – Sep 30, 2017

Evaluation of Two Different Treatments for Lower Pore Renal Stone: Microperc Vs FURS

To evaluate the merits of Microperc and RIRS for the treatment for lower pole renal stone between 10-20 mm. Investigators will do a multi-centers randomized controlled trial(RCT). A total of 200 (three hundred) patients, aging between 18 and 60 year...
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US Clinical Trial NCT03413449 – NIH – Jan 16, 2018

Frailty in Thoracic Surgery

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US Clinical Trial NCT03469375 – NIH – Mar 12, 2018

Modified-FOLFIRINOX Regimen Based Neoadjuvant Therapy in Chinese Patients With Locally Advanced Pancreatic Cancer

At this institution, a mFOLFIRINOX regimen has been adopted for metastatic pancreatic cancer (MPC) patients and promising results obtained. The modification resulted in a significantly reduced prevalence of severe adverse events in MPC patients, whe...
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US Clinical Trial NCT03597932 – NIH – Jun 22, 2018

Intraoperative Handover Checklist of Anesthesia Care Improves Postoperative Outcomes Among Patients Undergoing Major Surgery: a Multicenter, Before-after Cohort Study

Many retrospective studies have demonstrated that among adults undergoing major surgery, complete handover of intraoperative anesthesia care compared with no handover was associated with a higher risk of adverse postoperative outcomes. Anesthesiolog...
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US Clinical Trial NCT03468712 – NIH – Jan 23, 2018

Laparoscopic D2 Distal Gastrectomy Following Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancers: A Prospective Multicenter Trial

This is a prospective, multi-centers, open-label, single-arm study, and the aim of this trial is to evaluate the safety of laparoscopic distal D2 radical gastrectomy for the treatment of locally advanced gastric cancer (cT3-4a, N-/+, M0) after neoad...
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US Clinical Trial NCT03656263 – NIH – Aug 29, 2018

The Clinical Significance of Portal Hypertension After Cardiac Surgery

Hypothesis: Portal flow pulsatility detected by Doppler ultrasound during cardiac surgery is an echographic marker of cardiogenic portal hypertension from right ventricular failure and is associated with adverse clinical outcomes. Background: Peri-...
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