Searching for keyword:"Green tea"

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US Clinical Trial NCT00383058 – NIH – Sep 29, 2006

The Extract of Green Tea on Obese Women: a Randomized Double Blindness Clinical Trial

We conducted the pilot study in 2005. The initial findings showed the extract of green tea is benefit on obese women. The potential benefit include appetite lowing, lipid markers decreasing and regulating balance of obese related hormone peptides. S...
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US Clinical Trial NCT02891538 – NIH – Aug 31, 2016

A Pilot Study to Evaluate the Chemopreventive Effects of Epigallocatechin Gallate (EGCG) in Colorectal Cancer (CRC) Patients With Curative Resections.

Part 1: Blood draw prior to surgery, followed by surgical resection, and surgical pathologic specimen will be archived. After surgery, patient will be seen in 4-12 weeks to determine if adjuvant chemotherapy is indicated, in which case patient will...
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US Clinical Trial NCT01687556 – NIH – Jul 23, 2010

Epigallocatechin-3-Gallate Improves Acne in Humans by Modulating Intracellular Molecular Targets and Inhibiting P. Acnes

Acne vulgaris is one of the most prevalent skin disorders of sebaceous follicles, affecting more than 85% of adolescents in United States. Acne can persist throughout the adulthood, and even a mild form of acne might progress to permanent scarring o...
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US Clinical Trial NCT01187147 – NIH – Aug 20, 2010

Effects of Green Tea Extract (GTE) on Systemic Oxidative and Antioxidative Status in Chinese Patients With Stable Asthma

1. Background Asthma constitutes a significant health problem both in Hong Kong and worldwide (1). Different risk factors for asthma have been identified. These include atopy (2), family history of asthma, exposure to indoor aeroallergens (3) air p...
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US Clinical Trial NCT00461942 – NIH – Apr 17, 2007

A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study to Assess the Neuroprotection Effect of Green Tea Polyphenol in De Novo Parkinson's Disease Patients

The primary outcome measurement is UPDRS using a delay start design. Total 480 de novo PD patients divided into three dosage groups of green tea polyphenol and one placebo control group. Patients will be treated for one year.
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US Clinical Trial NCT01846338 – NIH – May 1, 2013

The Effect of「GTT-EGCG」on Acne Women

change in acne lesions counts, hormone, quality of life
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US Clinical Trial NCT00153790 – NIH – Sep 7, 2005

The Effect of Soy Lecithin-derived N-oleoyl-phosphatidyl-ethanolamine (NOPE) and Green Tea-derived Epigallocatechin Gallate (EGCG) on Indices of Weight Loss and Appetite Suppression

Participants will be randomized to either a control or treatment group taking the dietary supplement containing a soy lecithin-derived N-oleoyl-phosphatidyl-ethanolamine (NOPE) and caffeine free Green Tea-derived epigallocathchin gallate (EGCG) whos...
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US Clinical Trial NCT02077660 – NIH – Feb 12, 2014

The Effect of Green Tea on Anthropometric, Oxidation and Inflammation Parameters in Physically Active Elderly Compared to Sedentary Elderly

A prospective, crossover trial in which every individual served its own control. All subjects undergo a four weeks washout period, during which they briefed to avoid tea drinking and antioxidant supplements until the end of the study. At the end of...
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US Clinical Trial NCT00934908 – NIH – Jul 6, 2009

Prevention of Weight Gain and Dyslipidemia by Green Tea in Patients Initiating Therapy With Olanzapine

Atypical antipsychotic (AA) medications are associated with obesity, diabetes mellitus, dyslipidemia, and cardiovascular disease.1 The prevalence of obesity in the AA medicated population ranges from 40-60%, compared to 30% of the general population...
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US Clinical Trial NCT01484912 – NIH – May 9, 2007

A Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy and Safety of STA-2 in Patients With Chronic Stable Angina

The primary objective of this study was to evaluate the efficacy of STA-2 in the management of chronic stable angina. The secondary objectives of this study were to evaluate the safety and pharmacological activities of STA-2 in the management of chr...
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US Clinical Trial NCT01018615 – NIH – Nov 20, 2009

Steady-State Pharmacokinetic Interactions of Green Tea Catechins and Silymarin Flavonolignans in Treatment Naïve Patients With Chronic Hepatitis C Infection

Silymarin and green tea are the two most widely used botanical products used by patients with chronic hepatitis C virus (HCV) infection. A major limitation of prior clinical investigations that may account for lack of efficacy is their use of inadeq...
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US Clinical Trial NCT00718094 – NIH – Jul 16, 2008

A Phase IIa Pilot Study to Determine the Safety of an Oral Dose of Green Tea Extract (Polyphenon E®) and Provide Preliminary Evidence to Support Its Efficacy in Ulcerative Colitis

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US Clinical Trial NCT01248143 – NIH – Nov 24, 2010

Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases

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US Clinical Trial NCT00567905 – NIH – Dec 4, 2007

Effect of Green Tea Extract on Type 2 Diabetes: a Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Green tea is one of the most popular beverages in the world. It is believed to have beneficial effects in prevention and treatment of many diseases, one of which is anti-obesity and anti-diabetes. The benefit effects of green tea are mainly attribu...
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US Clinical Trial NCT00718653 – NIH – Jul 17, 2008

Effects of Antioxidants on Human Macular Pigments

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US Clinical Trial NCT01594086 – NIH – May 1, 2012

Effects of Green Tea Consumption on Homocysteine Metabolism and Cognitive Dysfunction in Elderly: An Exploratory Clinical Study

Elderly people with impaired cognitive function go on increasing year by year with the coming aged society. Among them, the Alzheimer disease is a major cause of the illness, which is progressively worse, has no fundamental curable therapy, and indu...
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US Clinical Trial NCT02627898 – NIH – Dec 3, 2015

Effect of Green Tea Extract Administration on Arterial Stiffness in Patients With Type 2 Diabetes Mellitus

The objetive is to evaluate the effect of administration of Green tea exctract on arterial stiffness in individuals with T2DM. The investigators will conduct a double-blind trial, randomized, placebo control group, each group 12 male and female pati...
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US Clinical Trial NCT01167673 – NIH – Jul 21, 2010

A Double Blind Placebo Controlled Cross Over Study for the Use of Coltect (Green Tea, Selenium and Curcumin) in Irritable Bowel Syndrome

The etiology of Irritable bowel syndrome is unknown but some evidence suggests it may be caused by a certain degree of inflammation, another theory is that intestinal flora has an influence on IBS. Coltect combines 3 ingredients: green tea, selenium...
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US Clinical Trial NCT00692731 – NIH – Jun 4, 2008

A Randomized, Double-Blind, Controlled Study to Assess the Efficacy of a Tea Catechin Sports Drink for Enhancing Exercise-Induced Fat Loss

The study will include two screening/baseline visits and six treatment visits over 12 weeks. During the treatment phase of the study, subjects will be instructed to consume one bottle of sports drink (500 ml) daily (total consumption of tea catechin...
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US Clinical Trial NCT02321969 – NIH – Dec 17, 2014

Green Tea Extracts for the Prevention of Colorectal Adenomas and Colorectal Cancer

The subjects who had undergone complete removal of colorectal adenomas by endoscopic polypectomy have been enrolled since June 2010. They were then randomized into two groups as follows: supplementation group (0.9 g GTE per day for 12 months) or con...
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US Clinical Trial NCT02147041 – NIH – Jan 20, 2014

The Effect of Extract of Green Tea on Obese Women Obese Related Hormone Peptides

Obesity has become a noticeable and worldwide public health problem recently. According to the WHO survey in 2005, 1.6 billion and 400 million adults were found overweight and obese, respectively. In Taiwan, there are more than 30% found overweight...
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US Clinical Trial NCT00302289 – NIH – Mar 13, 2006

B181: Stimulation of Thermogenesis by Bio-Active Food Ingredients

Background: Long-term weight maintenance of a weight loss is often unsuccessful. Often a weight regain is observed in most studies that could indicate that most subjects are not able to change their eating habits. There is a need for simple and safe...
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US Clinical Trial NCT01417312 – NIH – Aug 15, 2011

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US Clinical Trial NCT03053882 – NIH – Feb 4, 2017

Comparative Study of the Effects of Green Tea and Peppermint Herbal Mouthwash on Halitosis.

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US Clinical Trial NCT01082302 – NIH – Feb 1, 2010

An Open-Label, Single-Center Phase I (Phase IV/ USA) Study to Assess the Pharmacokinetic Profile of Topically Applied Veregen® 15% in Patients With External Genital and Perianal Warts Compared With Oral Intake of a Green Tea Beverage

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US Clinical Trial NCT00363805 – NIH – Aug 10, 2006

Chemoprevention of Lung Carcinogenesis Using Green Tea: Phase IIb Randomized, Double-Blinded, Placebo Controlled Trial of Green Tea and Polyphenon E in Former Smokers With Chronic Obstructive Lung Disease (COPD)

OBJECTIVES: Primary - Evaluate the effects of high-level oral consumption of defined green tea (four 12-oz servings/day) or polyphenon E capsules (4 capsules/day) on markers of cellular oxidative damage, as measured by 8-hydroxydeoxyguanosine (8-O...
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US Clinical Trial NCT02542449 – NIH – Sep 1, 2015

Placebo Controlled, Randomized, Single Blinded Trial on the Effects of Greenselect Phytosome® on Weight Maintenance in Obese Women After a 3-month Weight Loss Intervention

Most obese subjects regain weight after weight loss due to compensatory adaptations finalized to maintain stable body energy stores. In lean or obese individuals, maintenance of a 10% or greater reduction in body weight is associated with a decline...
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US Clinical Trial NCT02545244 – NIH – Sep 7, 2015

"Effectiveness of Black Tea Mouthwash on Plaque Formation:A Randomized Controlled Clinical Trial"

The study titled "Effectiveness of Black Tea Mouthwash on Plaque formation: A Randomized Controlled Clinical Trial" conducted at Department of Periodontics,during February 2015 till July 2015 included three interventional arms with 15 subjects each...
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US Clinical Trial NCT02779361 – NIH – May 18, 2016

Effect of Tea Consumption on Steroid Profile in Healthy Volunteers. Pilot Study

Anabolic androgenic steroids are included in the list of banned substances in sports by the World Anti-Doping Agency (WADA) because of its ability to improve the performance of athletes. Testosterone glucuronization by UGT2B17 isoenzyme (Uridine Di...
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US Clinical Trial NCT01628705 – NIH – May 17, 2012

Moderated-fat Diet Complemented With Green Tea Reduces oxLDL and Fat Mass in Obese Women: A Randomized, Controlled Clinical Trial

The investigators assessed 114 women with the eligibility criteria: obese women older than 18y, in good health, as determined by a medical history questionnaire, and normal results of clinical laboratory tests excluding lipids. Exclusion criteria wa...
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US Clinical Trial NCT01032031 – NIH – Dec 14, 2009

The Effect of Dietary Bioactive Compounds on Skin Health in Humans in Vivo

There is little information on the effect of oral catechin, a nutritionally relevant bioactive compound, on skin health in humans in vivo despite considerable evidence for protective effects in experimental studies. Vitamin C is essential for skin h...
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US Clinical Trial NCT01183767 – NIH – Aug 17, 2010

Sunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is the most frequent neuromuscular condition to occur in childhood and youth. The course of the disease is progressive, and life expectancy is severely curtailed by the participation of the respiratory muscles and/o...
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US Clinical Trial NCT00302263 – NIH – Mar 13, 2006

B181 Metobes-III: Weight Loss Maintenance of a New Bioactive Compound (Metobes-Long)

Subjects 22 healthy Danish overweight to obese men (BMI between 25 and 35 kg/m2), 18 to 50 years of age. All subjects must be weight stable (within  3-kg) 2 months prior to study inclusion, non-smoking, non-athletic and have no daily use of medicat...
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US Clinical Trial NCT01360567 – NIH – May 20, 2011

Taipei City Hospital, Taipei, Taiwan

Percent change Homa insulin resistance, cholesterol and triglycerol.
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US Clinical Trial NCT00793130 – NIH – Nov 16, 2008

The Efficacy and Tolerability of Coltect as Add-on in Patients With Active Ulcerative Colitis - an Open Label

Studies in animal models of colitis and in humans with IBD demonstrated that the components of Coltect have anti-inflammatory effects: Hanai H. et al demonstrated that curcumin was safe and effective in maintaining remission in patients with quiesc...
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US Clinical Trial NCT03628937 – NIH – Jul 10, 2018

The Effect of Decaffeinated Green Tea Polyphenol Intake on the Risk of Precocious Puberty Among Obese Girls

Simple obese girls are prone to premature or early puberty. The topic proposed based on previous studies, recruiting of 200 simple obesity girls, aged 7 to 10 years old. After the informed consent, they will be randomly divided into intervention gro...
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US Clinical Trial NCT01363869 – NIH – May 31, 2011

Effects of Green Tea on Level of Serum Uric Acid in Healthy Individuals

Elevated serum uric acid is related to the risk of development of gout, the most common inflammatory arthritis in men. Allopurinol, a xanthine oxidase inhibitor, is one of the uric-lowering agents commonly used in patients suffering from recurrent a...
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US Clinical Trial NCT01433289 – NIH – Sep 9, 2011

Placebo-Controlled, Dose-Blinded, Dose Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics and Antiviral Activity of Polyphenon E (EGCG) as Monotherapy for 14 Days in Antiretroviral Naïve and Experienced, HIV-1-Infected Subjects

HIV-1 infection ultimately results in impaired specific immune function by virtue of the initial binding of the HIV-1 virion envelope glycoprotein 120 (gp120) to the CD4 receptor in complex with a chemokine receptor on the T-cell surface1. Even thou...
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US Clinical Trial NCT03622762 – NIH – Aug 6, 2018

Effect of the Administration of Green Tea Extract on Soluble RAGE and Kidney Disease in Patients With Diabetes Mellitus Type 2

The objective of the study is to evaluate the effect of the administration of green tea extract on soluble RAGE and renal damage in patients with Type 2 Diabetes Mellitus, by means of a clinical trial, double blind, with randomization and placebo co...
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US Clinical Trial NCT00449982 – NIH – Mar 20, 2007

A Randomized, Double-Blind, Three-Arm Parallel-Group, Placebo-Controlled Phase 3 Trial to Investigate the Clinical Efficacy and Safety of Polyphenon E in the Treatment of External Genital Warts

External genital warts are non-malignant tumors caused by infections of the human papillomavirus (HPV), mainly types 6 and 11. Genital wart infections have one of the fastest growing incidence rates of all sexually transmitted diseases, with about 1...
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US Clinical Trial NCT01451723 – NIH – Oct 11, 2011

Phase 2 Randomized Placebo Controlled Trial of Polyphenon E in MS

This will be a double blind placebo controlled trial of Polyphenon E as a treatment for MS. The primary outcome will be the changes in NAA levels over one year. Secondary outcomes will be changes in brain atrophy over one year. As an exploratory ou...
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US Clinical Trial NCT01662232 – NIH – Aug 7, 2012

The Role of EGCG in Different Application Forms on Flow-mediated Dilation in Healthy Volunteers

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US Clinical Trial NCT01857258 – NIH – May 16, 2013

Green Tea Confections For Managing Postprandial Hyperglycemia-Induced Vascular Endothelial Dysfunction

The study involves validating a green tea confection (i.e. "gummy" candy) as a dietary strategy to attenuate postprandial hyperglycemia-induced impairments in vascular function. The central hypothesis is that a green tea confection will protect agai...
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US Clinical Trial NCT02011451 – NIH – Dec 10, 2013

Safety and Neuroprotective Effects of Theaphenon 95% (95% Pure EGCG) in Multiple Sclerosis

This will be a double blind placebo controlled trial of Theaphenon 95% (95% pure Epigallo-catechin-galleate [EGCG]) as a treatment for MS. The primary outcome will be the changes in N-Acety-Aspartate (NAA) levels over six months. Secondary outcomes...
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US Clinical Trial NCT00721890 – NIH – Jul 23, 2008

Phase II Study: Green Tea Intake for the Maintenance of Complete Remission in Women With Advanced Ovarian Carcinoma

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US Clinical Trial NCT01225770 – NIH – Oct 19, 2010

Effects of Gargling With Green Tea on Preventing Influenza Infection Among High School Students: A Randomized Clinical Study

Influenza infection is the principal cause of acute respiratory illnesses and occurs in epidemic or pandemic worldwide. It spreads easily among high school students and from them to the rest of the community; therefore the prevention of influenza is...
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US Clinical Trial NCT00933647 – NIH – Jul 6, 2009

Effects of Yerba Mate and Green Tea Consumption on Cardiovascular Risk Factors in Dyslipidemic and Overweight Subjects

Recommendations of lifestyle and dietary content changes are often made for primary prevention and improvement of many health conditions, including cardiovascular disease. For centuries, green tea (Camellia sinensis) has been linked to good health....
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US Clinical Trial NCT00302276 – NIH – Mar 13, 2006

Weight Loss Maintenance of a New Bioactive Compound (Metobes-Long)

It has previously been shown that a combination of tyrosine, capsaicin, catechines, and caffeine may stimulate the sympathetic nervous system and promote satiety, lipolysis and thermogenesis. In addition, dietary calcium may increase fecal fat excre...
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US Clinical Trial NCT03248115 – NIH – Aug 7, 2017

Bioavailability of Green Tea and Coffee Polyphenols in Healthy Participants

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US Clinical Trial NCT03973996 – NIH – May 30, 2019

Gut-level Antiinflammatory Activities of Green Tea in Metabolic Syndrome

Tea is the most abundantly consumed prepared beverage in the world. Green tea, containing catechins, exerts antiinflammatory activities. However, a fundamental gap exists concerning its intestinal-level targets that can prevent metabolic syndrome (M...
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